The TNFRSF10A Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to TNFRSF10A. This antibody recognizes Human antigen. The TNFRSF10A Antibody has been validated for the following applications: ELISA, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, and Western Blot.
Description
Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B